General Cell Lines and Cell Cultures
Biochain Institute Inc Paraffin Tissue Section - Human Uterus Tumor: Endometrium Adenocarcinoma, 5 sides/PK
BioChain's tissue products are based on the sample repository network established following the IRB-approved ethical standard and procedures. BioChain's formalin fixed paraffin embedded (FFPE) tissue section line encompasses a large selection of tissue sections which are suitable for immunohistochemistry and in situ hybridization assays. The tissue sections are approximately 5 um thick. Each slide contains tissue from a single human tumor. Documentation of tissues' clinical histories may be available upon request. For those customers who want to perform FFPE DNA and RNA isolation, BioChain can provide tissue section slices in tubes instead of mounting them on glass slides.
Eurofins Discoverx KILR Hut78 Cell Pool, 2 vials. (97-1024P037)
The KILR Hut78 cell pool is a stable, engineered target cell pool, which closely reflects the heterogeneous native protein expression of tumor environments, used to measure direct cell death mediated by immunooncology treatments (e.g. checkpoint modulators, bispecifics, CAR-T, etc.) via Antibody Dependent Cell-mediated Cytotoxicity (ADCC), Complement Dependent Cytotoxicity (CDC), and Antibody Dependent Cell Phagocytosis (ADCP). This product uses EFC technology. The cell pool is a heterogeneous population of Hut78 cells that overexpress a ProLabel-tagged housekeeping gene. Upon effector cells-mediated cell lysis, ProLabel is released to the media, where EA in the detection kit produces an EFC signal proportional to the level of ProLabel released. This allows for calculation of percent lysis of the KILR cell pool. This stable cell pool is provided as two vials of cryopreserved cells. For detailed product information, User Manual and datasheet, visit www.discoverx.com/kilr.
ATCC Quantitative Genomic DNA from; Escherichia coli; Strain: AMC 198
ATCC Genuine Nucleics can be used for assay development, verification, validation, monitoring of day-to-day test variation, and lot-to-lot performance of molecular-based assays. The quantitative format allows for the generation of a standard curve for quantitative PCR (qPCR) to determine bacterial load.
Revvity Health Sciences Inc cAMPZen Frozen Human Adenosine A2B Cell Line, HEK293 Cells
cAMPZen Frozen Human Adenosine A2B Cell Line, HEK293 Cells
ATCC PC-12 Adh; Pheochromocytoma; Rat (Rattus norvegicus)
PC-12 Adh is a polygonal-like cell that was isolated from the adrenal gland of a pheochromocytoma patient. This cell line was deposited by B Patterson.
Genscript Corporation CHO-K1/CD40 Stable Cell Line
Cluster of differentiation 40 CD40 is a costimulatory protein found on antigen presenting cells and is required for their activation The binding of CD154 (CD40L) on TH cells to CD40 activates antigen presenting cells and induces a variety of downstream effects
ATCC PfizerPneumococcal polysaccharide powder Type 3 (d3) 10mg
Purified pneumococcal polysaccharide type 3 is manufactured by Pfizer, Inc., for small-quantity distribution by ATCC. The pneumococcal powder type 3 is a component of the current 13-valent vaccine against Streptococcus pneumoniae. The pneumococcal polysaccharide type 3 can be used to assay for type-specific antibodies, research immune responses, and study immunodeficiencies.
ATCC Kasumi-3; Acute Myeloblastic Leukemia; Human (Homo sapiens)
Kasumi-3 is a lymphoblast cell line that was isolated in 1990 from the peripheral blood of an Asian, 57-year-old, male patient with acute myeloblastic leukemia. This cell line was deposited by H Asou and can be used in immunology and immune system disorder research.
ATCC Bacteroides fragilis
Bacteroides fragilis strain VPI 2553 [EN-2; NCTC 9343] is a type strain that was isolated from an appendix abscess. This whole-genome sequenced strain can be used in media testing, quality control, and pharmaceutical testing.
ATCC Mycoplasma gallisepticum
Mycoplasma gallisepticum strain [NCTC 10115, PG 31, X95] is bacterial type strain that was isolated from a suspension of tracheal and airsac tissues from chickens with chronic respiratory disease. This product has applications in media testing, quality control, and agricultural research.
Brainxell Inc Spinal Motor Neurons (Human iPSC-Derived, Male Line, 1M)
Human spinal motor neurons derived from iPSC line WC-30, male. Contents: 1 vial of ≥1x10^6 viable cryopreserved cells. Marker Expression: Spinal Motor Neurons (BX-0100) have high neuronal purity (>80%) and consist of greater than 70% motor neurons. Labeling with the pan-neuronal marker MAP2 (green) and the motor neuron-specific marker FOXP1 (red) highlights the purity of this neuronal product. Function: Spinal Motor Neurons exhibit pronounced electrophysiological activity after two weeks in culture, as demonstrated by multi-electrode array (MEA) recordings. Related diseases: Amyotrophic Lateral Sclerosis (ALS), Spinal muscular atrophy (SMA), & Spinal Cord Injury. Primary neurotransmitter released: Acetylcholine
Eurofins Discoverx PathHunter U2OS BLK Activity Assay, 2 vials. (93-0882C3)
The PathHunter U2OS BLK Activity Assay is a stable, engineered cell line for use in studying small molecule drug candidates targeting the BLK kinase domain. The cell line is engineered to express the catalytic domain from BLK fused to the cytokine receptor binding domain (CRBD) of JAK2. The cells co-express an Enzyme Acceptor (EA) tagged SH2 domain and a ProLink (PK) tagged Cytokine receptor. The CRBD is designed to bind the CTK catalytic domain to the GHR-PK. Activation of the GHR-PK induces receptor phosphorylation by the BLK catalytic domain. This leads to SH2-EA recruitment and production of EFC signal. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, User Manual and datasheet, visit www.discoverx.com/kinases.
ATCC Bacillus cereus; 6 x 0.3mL
ATCC 10876-MINI-PACK™ consists of 6 ready-to-use vials of ATCC 10876™ frozen in 200 μL of glycerol stock, eliminating the need to rehydrate and culture the strain prior to use. Each vial is provided with a 2-D barcode for easy storage and tracking, as well as peel-off labels for fast and reliable recordkeeping.
Eurofins Discoverx PathHunter U2OS EpoR-JAK2 Functional Assay, 2 vials. (93-0900C3)
The PathHunter EpoR-JAK2 Functional assay cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting CTKs. This cell line enables assessment of EpoR activation via detection of JAK2 mediated phosphorylation-induced SH2 domain protein recruitment. This product uses EFC technology. The included cell line overexpresses ProLink-tagged EpoR cytokine receptor, an untagged CTK JAK2 and EA-tagged SH2 domain protein. Upon activation of the cytokine receptor, CTK-based receptor phosphorylation leads to SH2-EA recruitment and production of EFC signal. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, User Manual and datasheet, visit www.discoverx.com/kinases.
Eurofins Discoverx PathHunter CHO-K1 mFPR2 β-Arrestin Cell Line, 2 vials. (93-1034C2)
The PathHunter mFPR2 cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. formylpeptides) based activation of mFPR2 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged mFPR2 and EA-tagged β-Arrestin-2. Activation of mFPR2 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. This stable modified cell line is provided as two vials of cryopreserved cells. Please note that this product expresses the Mouse version of this protein. For detailed product information, User Manual and datasheet, visit www.discoverx.com/gpcr.